| Kolo | Datum/Vreme | Utakmica | Rezultat |
|---|---|---|---|
| 1 | 22.08.2021 10:00 | AF Đokić - Smederevo 1924 | 0:4 |
| 2 | 29.08.2021 10:00 | Smederevo 1924 - VGSK | 7:1 |
| 3 | 05.09.2021 10:00 | Plana - Smederevo 1924 | 1:0 |
| 4 | 12.09.2021 10:00 | Smederevo 1924 - OPK Rudar 1933 | 2:0 |
| 5 | 19.09.2021 10:00 | Sloga 33 - Smederevo 1924 | 4:1 |
| 6 | 26.09.2021 10:00 | Jasenica 2017 - Smederevo 1924 | 0:1 |
| 7 | 02.10.2021 09:30 | Smederevo 1924 - Petlić SD 2006 | 1:1 |
| 8 | 10.10.2021 10:00 | Cepelin 026 - Smederevo 1924 | 2:0 |
| 9 | 17.10.2021 10:00 | Smederevo 1924 - Zvižd | 11:1 |
| 10 | 20.10.2021 10:00 | Železničar - Smederevo 1924 | 4:2 |
| 11 | 24.10.2021 10:00 | Smederevo 1924 - RSK | 0:5 |
| 12 | 31.10.2021 10:00 | AF Duljaj - Smederevo 1924 | 2:1 |
| 13 | 07.11.2021 10:00 | Smederevo 1924 - Soko 2015 | 4:0 |
| 14 | 14.11.2021 10:00 | Mladi radnik 1926 - Smederevo 1924 | 2:1 |
| 15 | 21.11.2021 10:00 | Smederevo 1924 - Šumadija | 3:0 |
| 16 | 19.03.2022 11:00 | Smederevo 1924 - AF Đokić | 6:0 |
| 17 | 26.03.2022 10:00 | VGSK - Smederevo 1924 | 2:2 |
| 18 | 02.04.2022 10:00 | Smederevo 1924 - Plana | 0:0 |
| 19 | 09.04.2022 10:00 | OPK Rudar 1933 - Smederevo 1924 | 2:0 |
| 20 | 16.04.2022 10:00 | Smederevo 1924 - Sloga 33 | 0:1 |
| 21 | 23.04.2022 10:00 | Smederevo 1924 - Jasenica 2017 | 2:1 |
| 22 | 30.04.2022 10:00 | Petlić SD 2006 - Smederevo 1924 | 2:3 |
| 23 | 04.05.2022 10:00 | Smederevo 1924 - Cepelin 026 | |
| 24 | 07.05.2022 10:00 | Zvižd - Smederevo 1924 | 1:4 |
| 25 | 14.05.2022 10:00 | Smederevo 1924 - Železničar | 6:1 |
| 26 | 21.05.2022 10:00 | RSK - Smederevo 1924 | |
| 27 | 28.05.2022 10:00 | Smederevo 1924 - AF Duljaj | 0:4 |
| 28 | 04.06.2022 10:00 | Soko 2015 - Smederevo 1924 | 1:5 |
| 29 | 08.06.2022 10:00 | Smederevo 1924 - Mladi radnik 1926 | 5:1 |
| 30 | 11.06.2022 10:00 | Šumadija - Smederevo 1924 | 2:2 |
| Poz | Tim | Utak | Pob | Ner | Por | DG | PG | GR | Forma | Bod | |
| 1 | AF Duljaj | 28 | 24 | 3 | 1 | 146 | 19 | +127 | 1 1 1 1 1 | 75 | |
| 2 | OPK Rudar 1933 | 28 | 16 | 3 | 9 | 66 | 36 | +30 | 1 1 2 1 1 | 51 | |
| 3 | Sloga 33 | 28 | 15 | 6 | 7 | 70 | 46 | +24 | 2 1 X 1 1 | 51 | |
| 4 | Plana | 28 | 14 | 5 | 9 | 76 | 34 | +42 | 1 X 1 1 1 | 47 | |
| 5 | Smederevo 1924 | 28 | 14 | 4 | 10 | 73 | 41 | +32 | 1 2 1 1 X | 46 | |
| 6 | RSK | 15 | 14 | 0 | 1 | 96 | 10 | +86 | 1 1 2 1 1 | 42 | |
| 7 | Petlić SD 2006 | 28 | 12 | 5 | 11 | 85 | 74 | +11 | 1 1 2 1 2 | 41 | |
| 8 | Mladi radnik 1926 | 28 | 13 | 2 | 13 | 85 | 83 | +2 | 2 2 X 2 1 | 41 | |
| 9 | Šumadija | 28 | 12 | 4 | 12 | 66 | 68 | -2 | 1 X 1 2 X | 40 | |
| 10 | Cepelin 026 | 15 | 12 | 2 | 1 | 85 | 18 | +67 | 1 2 1 X 1 | 38 | |
| 11 | Železničar | 28 | 10 | 5 | 13 | 61 | 89 | -28 | 2 2 2 1 2 | 35 | |
| 12 | Jasenica 2017 | 28 | 11 | 2 | 15 | 52 | 83 | -31 | X 1 1 1 2 | 35 | |
| 13 | AF Đokić | 28 | 7 | 5 | 16 | 41 | 107 | -66 | X X 2 2 2 | 26 | |
| 14 | VGSK | 28 | 6 | 3 | 19 | 46 | 114 | -68 | 2 X 2 2 2 | 21 | |
| 15 | Soko 2015 | 28 | 4 | 1 | 23 | 25 | 140 | -115 | 2 2 2 2 2 | 13 | |
| 16 | Zvižd (-1) | 28 | 1 | 2 | 25 | 20 | 131 | -111 | 2 2 2 2 2 | 4 | |
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